Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils

@inproceedings{Alba2012TranscriptionOL,
  title={Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils},
  author={Gonzalo Alba and Mar{\'i}a Edith Reyes and Consuelo Santa-Mar{\'i}a and Remedios Ram{\'i}rez and Isabel Geniz and J. Villar Jim{\'e}nez and Jos{\'e} Mart{\'i}n-Nieto and El{\'i}zabeth Pintado and Francisco Sobrino},
  booktitle={PloS one},
  year={2012}
}
Liver X receptors (LXRs) are ligand-activated transcription factors of the nuclear receptor superfamily. They play important roles in controlling cholesterol homeostasis and as regulators of inflammatory gene expression and innate immunity, by blunting the induction of classical pro-inflammatory genes. However, opposite data have also been reported on the… CONTINUE READING