Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1).

@article{Sarid1998TranscriptionMO,
  title={Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1).},
  author={Ronit Sarid and Ornella Flore and Roy A. Bohenzky and Yuan - Chia Chang Yeun - Chung Chang Chin - Chen Chang and Patrick S Moore},
  journal={Journal of virology},
  year={1998},
  volume={72 2},
  pages={1005-12}
}
Kaposi's sarcoma-associated herpesvirus (KSHV) gene transcription in the BC-1 cell line (KSHV and Epstein-Barr virus coinfected) was examined by using Northern analysis with DNA probes extending across the viral genome except for a 3-kb unclonable rightmost region. Three broad classes of viral gene transcription have been identified. Class I genes, such as those encoding the v-cyclin, latency-associated nuclear antigen, and v-FLIP, are constitutively transcribed under standard growth conditions… CONTINUE READING
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KSHV ORF K9 (v-IRF) is an oncogene that inhibits the interferon signaling pathway

  • Gao, S.-J, +4 authors P. S. Moore
  • Oncogene
  • 1997

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