Transcription initiation region of the srfA operon, which is controlled by the comP-comA signal transduction system in Bacillus subtilis.

@article{Nakano1991TranscriptionIR,
  title={Transcription initiation region of the srfA operon, which is controlled by the comP-comA signal transduction system in Bacillus subtilis.},
  author={Michiko M. Nakano and Lijun Xia and Peter Zuber},
  journal={Journal of bacteriology},
  year={1991},
  volume={173 17},
  pages={5487-93}
}
srfA is an operon required for the production of the lipopeptide antibiotic surfactin, competence development, and efficient sporulation in Bacillus subtilis. The expression of srfA is induced after the end of exponential growth and is dependent on the products of late-growth regulatory genes comP, comA, and spo0K. To begin to understand the mechanism of srfA regulation, the srfA promoter region was identified and characterized. To examine srfA promoter activity, the srfA promoter was fused to… CONTINUE READING