Transcription factors mediate long-range enhancer – promoter interactions

  • Ilias K. Nolisa, Daniel J. McKayb, +3 authors Dimitris Thanosa
  • Published 2009
We examined how remote enhancers establish physical communication with target promoters to activate gene transcription in response to environmental signals. Although the natural IFNenhancer is located immediately upstream of the core promoter, it also can function as a classical enhancer element conferring virus infection-dependent activation of… CONTINUE READING