Transcription factors CTCF and Pax6 are segregated to different cell types during retinal cell differentiation.

@article{CantoSoler2008TranscriptionFC,
  title={Transcription factors CTCF and Pax6 are segregated to different cell types during retinal cell differentiation.},
  author={M Valeria Canto-Soler and Hu Huang and Mar{\'i}a Soledad Romero and Ruben Adler},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2008},
  volume={237 3},
  pages={758-67}
}
We have hypothesized that the transcription factor CTCF may influence retinal cell differentiation by controlling Pax6 expression, because (1) CTCF has been shown to repress Pax6 expression in some tissues, and (2) Pax6 blocks the differentiation of retinal progenitor cells as photoreceptors and promotes their differentiation as nonphotoreceptor neurons… CONTINUE READING