Transcription factors: from enhancer binding to developmental control

@article{Spitz2012TranscriptionFF,
  title={Transcription factors: from enhancer binding to developmental control},
  author={François Spitz and Eileen E. M. Furlong},
  journal={Nature Reviews Genetics},
  year={2012},
  volume={13},
  pages={613-626}
}
Developmental progression is driven by specific spatiotemporal domains of gene expression, which give rise to stereotypically patterned embryos even in the presence of environmental and genetic variation. Views of how transcription factors regulate gene expression are changing owing to recent genome-wide studies of transcription factor binding and RNA expression. Such studies reveal patterns that, at first glance, seem to contrast with the robustness of the developmental processes they encode… 

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