Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression

@inproceedings{Sun2018TranscriptionFP,
  title={Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression},
  author={Xiaoji Sun and Xuya Wang and Zuojian Tang and Mark Grivainis and David John Kahler and Chi Y. Yun and Paolo Mita and David Feny{\"o} and Jef D. Boeke},
  booktitle={Proceedings of the National Academy of Sciences of the United States of America},
  year={2018}
}
Transposable elements (TEs) represent a substantial fraction of many eukaryotic genomes, and transcriptional regulation of these factors is important to determine TE activities in human cells. However, due to the repetitive nature of TEs, identifying transcription factor (TF)-binding sites from ChIP-sequencing (ChIP-seq) datasets is challenging. Current… CONTINUE READING