Transcription factor expression in lipopolysaccharide-activated peripheral-blood-derived mononuclear cells.

@article{Roach2007TranscriptionFE,
  title={Transcription factor expression in lipopolysaccharide-activated peripheral-blood-derived mononuclear cells.},
  author={Jared C. Roach and Kelly D. Smith and Katie L Strobe and Stephanie M. Nissen and Christian D. Haudenschild and Daixing Zhou and Thomas J. Vasicek and Gerlinde Held and Gustavo Stolovitzky and Leroy E. Hood and Alan Aderem},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 41},
  pages={16245-50}
}
Transcription factors play a key role in integrating and modulating biological information. In this study, we comprehensively measured the changing abundances of mRNAs over a time course of activation of human peripheral-blood-derived mononuclear cells ("macrophages") with lipopolysaccharide. Global and dynamic analysis of transcription factors in response to a physiological stimulus has yet to be achieved in a human system, and our efforts significantly advanced this goal. We used multiple… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Cell Immunol

  • R Nilsson, VB Bajic, +10 authors T Ravasi
  • 2006

Stem Cells 25:771–778

  • JC Roach, G Glusman, +5 authors A Aderem
  • Annu Rev Genomics Hum Genet
  • 2005

Annu Rev Genomics Hum Genet

  • T Ideker, T Galitski, L Hood
  • 2001

Similar Papers

Loading similar papers…