Transcription factor effector domains.

  title={Transcription factor effector domains.},
  author={Seth E Frietze and Peggy J. Farnham},
  journal={Sub-cellular biochemistry},
The last decade has seen an incredible breakthrough in technologies that allow histones, transcription factors (TFs), and RNA polymerases to be precisely mapped throughout the genome. From this research, it is clear that there is a complex interaction between the chromatin landscape and the general transcriptional machinery and that the dynamic control of this interface is central to gene regulation. However, the chromatin remodeling enzymes and general TFs cannot, on their own, recognize and… CONTINUE READING


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