Transcription factor RTEF-1 mediates alpha1-adrenergic reactivation of the fetal gene program in cardiac myocytes.

@article{Stewart1998TranscriptionFR,
  title={Transcription factor RTEF-1 mediates alpha1-adrenergic reactivation of the fetal gene program in cardiac myocytes.},
  author={Andrew Francis Stewart and Joseph G Suzow and Toru Kubota and Takahisa Ueyama and Helen H. W. Chen},
  journal={Circulation research},
  year={1998},
  volume={83 1},
  pages={43-9}
}
Alpha1-adrenergic receptor stimulation induces cardiac myocytes to hypertrophy and reactivates many fetal genes, including beta-myosin heavy chain (betaMyHC) and skeletal alpha-actin (SKA), by signaling through myocyte-specific CAT (M-CAT) cis elements, binding sites of the transcriptional enhancer factor-1 (TEF-1) family of transcription factors. To examine functional differences between TEF-1 and related to TEF-1 (RTEF-1) in alpha1-adrenergic reactivation of the fetal program, expression… CONTINUE READING

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Transcriptional enhancer factor-1 is a transcriptional regulator in cardiac myocytes and vascular smooth muscle cells [abstract

AFR Stewart, M-H Disatnik, FD Fortuin, K Kariya, PC. Simpson
Circulation. 1995;91(suppl I):I-758. Stewart et al July • 1998

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