Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1

@inproceedings{Katto2013TranscriptionFN,
  title={Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1},
  author={Judith Katto and Nicole Maria Anna Adela Engel and Wasim Abbas and Georges Herbein and Ulrich Mahlknecht},
  booktitle={Clinical Epigenetics},
  year={2013}
}
The NAD-dependent protein deacetylase SIRT1 has a wide range of different targets, which may be regulated either directly through deacetylation and thus potentially altering their activity or localization or indirectly by deacetylation of histones, which in turn alters their transcription rate and availability. SIRT1 is therefore involved in the regulation… CONTINUE READING