Transcription factor ATF3 partially transforms chick embryo fibroblasts by promoting growth factor-independent proliferation

Abstract

Activating Transcription Factor 3 (ATF3) is a member of the bZip family of transcription factors. Previous studies in mammalian cells suggested that like other bZip family members e.g. Jun and Fos, ATF3 might play a role in the control of cell proliferation and participate in oncogenic transformation. To investigate this putative ATF3 function directly, the… (More)
DOI: 10.1038/sj.onc.1204200

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