Transcription factor 7-like 2 (TCF7L2) gene polymorphism and clinical phenotype in end-stage renal disease patients

@inproceedings{Buraczynska2014TranscriptionF7,
  title={Transcription factor 7-like 2 (TCF7L2) gene polymorphism and clinical phenotype in end-stage renal disease patients},
  author={Monika Buraczynska and Pawel Zukowski and Piotr Książek and Agata Kuczmaszewska and Joanna Janicka and Wojciech Zaluska},
  booktitle={Molecular Biology Reports},
  year={2014}
}
Variants of the transcription factor 7-like 2 gene (TCF7L2) have been associated with type 2 diabetes and cardiovascular disease in different populations. Here we investigated the potential association of the rs7903146 polymorphism in the TCF7L2 gene with clinical profile of end-stage renal disease (ESRD) patients. We examined a cohort of 1065 ESRD patients with diabetic and non-diabetic renal disease. The control group consisted of 924 healthy individuals. All subjects were genotyped for the… CONTINUE READING
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