Transcription elements and functional expression of proopiomelanocortin genes in the pituitary gland of the barfin flounder.

@article{Kobayashi2008TranscriptionEA,
  title={Transcription elements and functional expression of proopiomelanocortin genes in the pituitary gland of the barfin flounder.},
  author={Yuki Kobayashi and Hiroaki Chiba and Noriko Amiya and Takeshi Yamanome and Kanta Mizusawa and Masafumi Amano and Akiyoshi Takahashi},
  journal={General and comparative endocrinology},
  year={2008},
  volume={158 3},
  pages={259-67}
}
Proopiomelanocortin (POMC) is the precursor of adrenocorticotropin, melanocyte-stimulating hormone, and endorphin. Barfin flounder Verasper moseri possesses three POMC mRNAs. In this study, we determined the amino acid sequences of POMC-A, POMC-B, and POMC-C in this fish and investigated the effects of black or white background on the expression of these genes. The three POMC genes (POMCs) were composed of three exons and two introns, wherein all the hormonal segments were encoded on the third… CONTINUE READING

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