Transcription destabilizes triplet repeats.

  title={Transcription destabilizes triplet repeats.},
  author={Yunfu Lin and Leroy Hubert and John P. Wilson},
  journal={Molecular carcinogenesis},
  volume={48 4},
Triplet repeat expansion is the molecular basis for several human diseases. Intensive studies using systems in bacteria, yeast, flies, mammalian cells, and mice have provided important insights into the molecular processes that are responsible for mediating repeat instability. The age-dependent, ongoing repeat instability in somatic tissues, especially in… CONTINUE READING