• DOI:10.1038/nrg3001
Corpus ID: 21123216

Transcription by RNA polymerase III: more complex than we thought

@article{White2011TranscriptionBR,
  title={Transcription by RNA polymerase III: more complex than we thought},
  author={R. White},
  journal={Nature Reviews Genetics},
  year={2011},
  volume={12},
  pages={459-463}
}

R. White

Published 2011

Medicine, Biology

Nature Reviews Genetics

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RNA polymerase (Pol) III is highly specialized for the production of short non-coding RNAs. Once considered to be under relatively simple controls, recent studies using chromatin immunoprecipitation followed by sequencing (ChIP–seq) have revealed unexpected levels of complexity for Pol III regulation, including substantial cell-type selectivity and intriguing overlap with Pol II transcription. Here I describe these novel insights and consider their implications and the questions that remain.