Transcription-based COX-2 inhibition: a therapeutic strategy.

  • K. Y. K. Wu
  • Published 2006 in Thrombosis and haemostasis


Potent selective cyclooxygenase-2 (COX-2) inhibitors are effective in controlling inflammatory disorders but are associated with cardiovascular complications. Their clinical use has been severely limited. We propose that transcription-based inhibition of COX-2 expression represents a therapeutic strategy that may circumvent the undesired complications of… (More)


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@article{Wu2006TranscriptionbasedCI, title={Transcription-based COX-2 inhibition: a therapeutic strategy.}, author={K. Y. K. Wu}, journal={Thrombosis and haemostasis}, year={2006}, volume={96 4}, pages={417-22} }