Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

@article{Giovannetti2006TranscriptionAO,
  title={Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.},
  author={Elisa Giovannetti and Mario Del Tacca and V. Mey and Niccola Funel and Sara Nannizzi and Sergio Ricci and Cinzia Orlandini and Ugo Boggi and Daniela Campani and Marco Del Chiaro and Mauro Iannopollo and Generoso Bevilacqua and Franco Mosca and Romano Danesi},
  journal={Cancer research},
  year={2006},
  volume={66 7},
  pages={
          3928-35
        }
}
Gene expression analysis may help the management of cancer patients, allowing the selection of subjects responding to treatment. The aim of this study was the characterization of expression pattern of genes involved in gemcitabine activity in pancreas tumor specimens and its correlation with treatment outcome. The role of drug transport and metabolism on gemcitabine cytotoxicity was examined with specific inhibitors, whereas transcription analysis of human equilibrative nucleoside transporter-1… CONTINUE READING
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