Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation

@inproceedings{Slobodin2017TranscriptionIT,
  title={Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation},
  author={Boris Slobodin and Ruiqi Han and Vittorio Calderone and Joachim A. F. Oude Vrielink and Fabricio Loayza-Puch and Ran Elkon and Reuven Agami},
  booktitle={Cell},
  year={2017}
}
Transcription and translation are two main pillars of gene expression. Due to the different timings, spots of action, and mechanisms of regulation, these processes are mainly regarded as distinct and generally uncoupled, despite serving a common purpose. Here, we sought for a possible connection between transcription and translation. Employing an unbiased screen of multiple human promoters, we identified a positive effect of TATA box on translation and a general coupling between mRNA expression… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 112 times over the past 90 days. VIEW TWEETS
26 Citations
45 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Similar Papers

Loading similar papers…