Transcription Factor YY1 and Its Associated Acetyltransferases CBP and p300 Interact with Hepatitis Delta Antigens and Modulate Hepatitis Delta Virus RNA Replication

@article{Huang2008TranscriptionFY,
  title={Transcription Factor YY1 and Its Associated Acetyltransferases CBP and p300 Interact with Hepatitis Delta Antigens and Modulate Hepatitis Delta Virus RNA Replication},
  author={W. Huang and Ru-Tsun Mai and Y. Wu Lee},
  journal={Journal of Virology},
  year={2008},
  volume={82},
  pages={7313 - 7324}
}
  • W. Huang, Ru-Tsun Mai, Y. Wu Lee
  • Published 2008
  • Biology, Medicine
  • Journal of Virology
  • ABSTRACT Hepatitis delta virus (HDV) is a pathogenic RNA virus with a plant viroid-like genome structure. HDV encodes two isoforms of delta antigen (HDAg), the small and large forms of HDAg (SHDAg and LHDAg), which are essential for HDV RNA replication and virion assembly, respectively. Replication of HDV RNA depends on host cellular transcription machinery, and the exact molecular mechanism for HDV RNA replication is still unclear. In this study, we demonstrated that both isoforms of HDAg… CONTINUE READING
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