Transcription Factor Binding Site Mapping Using ChIP-Seq.

@article{Jaini2014TranscriptionFB,
  title={Transcription Factor Binding Site Mapping Using ChIP-Seq.},
  author={Suma Jaini and Anna Lyubetskaya and Antonio Gomes and Matthew Peterson and Sang Tae Park and Sahadevan Raman and Gary K. Schoolnik and James E. Galagan},
  journal={Microbiology spectrum},
  year={2014},
  volume={2 2}
}
Transcription factors (TFs) play a central role in regulating gene expression in all bacteria. Yet until recently, studies of TF binding were limited to a small number of factors at a few genomic locations. Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) provides the ability to map binding sites globally for TFs, and the scalability of the technology enables the ability to map binding sites for every DNA binding protein in a prokaryotic organism. We have developed a protocol for… 

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