Transcription: basal factors and activation.

  title={Transcription: basal factors and activation.},
  author={Jeffrey A Ranish and Steven Hahn},
  journal={Current opinion in genetics & development},
  volume={6 2},
Much progress has been made in the past few years in understanding the mechanism and regulation of mRNA synthesis. This rapid progress has largely been due to the availability of cloned genes encoding components of the transcription machinery. Structural and biochemical studies are rapidly defining the architecture of components in the transcription complex. Highly purified biochemical systems are beginning to elucidate the role of the individual initiation factors. The identification of a… CONTINUE READING

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