Transcription/replication collisions cause bacterial transcription units to be longer on the leading strand of replication

@article{Omont2004TranscriptionreplicationCC,
  title={Transcription/replication collisions cause bacterial transcription units to be longer on the leading strand of replication},
  author={Nicolas Omont and François K{\'e}p{\`e}s},
  journal={Bioinformatics},
  year={2004},
  volume={20 16},
  pages={2719-25}
}
MOTIVATION The costs of head-on versus codirectional collisions between the replication complex and the much slower transcription complex on the circular bacterial chromosomes are much debated. Although it is established that the number of genes on the leading strand is higher than on the lagging strand of replication, the consequences of collisions on the length of transcription units are unknown. RESULTS Here, we show that transcription units are generally longer on the leading strand, in… CONTINUE READING
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Prediction , distribution and evolution of intrinsic transcription terminators in bacterial genomes

  • T. Vermat, Y. Vandenbrouck, A. Viari, Y. d’Aubenton Carafa, C. Thermes
  • 2002

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