Transcription, translation and maturation of succinate dehydrogenase during cell cycle

  title={Transcription, translation and maturation of succinate dehydrogenase during cell cycle},
  author={B. Forde and P. John},
A STEPWISE accumulation of individual enzyme activities is a common feature of the eukaryotic cell cycle1. Two major hypotheses consider that the temporal restriction is produced by oscillatory repression or by linear reading of genes along the chromosome2,3. Both hypotheses, in their present form, assume that increase in enzyme activity is concurrent with transcription and translation. We have made use of the high degree of synchrony obtainable with Chlorella fusca var. vacuolata 211-8p, grown… Expand
In Chlorella and Chlamydomonas two periods of relatively constant duration determine total cell cycle length and cell size is stabilised by control of whether 2, 4, 8 or 16 daughter cells are formed by an influence of mother cell mass. Expand
Synthesis of the inner mitochondrial membrane and the intercalation of respiratory enzymes during the cell cycle of Chlorella.
It is concluded that mitochondrial growth involves the intercalation of periodically synthesized respiratory enzymes into membranes made earlier in the cycle, with consequent 5-fold changes in the density of active enzyme molecules in the membrane. Expand
Coupling of saxitoxin biosynthesis to the G1 phase of the cell cycle in the dinoflagellate Alexandrin fundyense: temperature and nutrient effects.
It is concluded that toxin biosynthesis in A. fundyense is coupled to the G1 phase of the cell cycle, that toxin synthesis is not down-regulated by phosphate deprivation and that interconversions among saxitoxin derivatives are influenced by the availability of phosphate. Expand
Cell cycle dynamics and the physiology of saxitoxin biosynthesis in Alexandrium fundyense (dinophyceae)
The aim of this thesis was to analyze novel aspects of toxigenesis and the cell cycle in Alexandrium and to apply molecular techniques to gain new insights on the regulation of STX biosynthesis. Expand
Veränderungen der Aktivitäten von Glutamatdehydrogenase, Malatdehydrogenase und Isocitratdehydrogenase im Verlauf des Wachstums batchvermehrter Zellsuspensionskulturen von Pisum unter Langtag- und Dauerdunkelbedingungen
Changes of the Specific Activities of Glutamate Dehydrogenase Malate Dehydrogenase and Isocitrate Dehydrogenase in Light- and Dark-Grown Suspension Cultures of Root Cells from Pisum sativum.


Control of de nova Isocitrate Lyase Synthesis in Chlorella
Two important hypotheses concerning the mechanism by which temporal restriction is imposed on the synthesis of enzymes during the cell cycle both suppose that enzyme synthesis occurs during a periodExpand
Stepwise accumulation of autoregulated enzyme activities during the cell cycle of the eucaryote Chlorella.
The intermittent increase in individual enzyme activities is discussed in terms of organelle synthesis and the rate of respiration during the cell cycle in a stepwise manner and held not to conform to the hypothesis of gene control by self-maintaining oscillations in feedback repression. Expand
Evidence for turnover of ribulose-1,5-diphosphate carboxylase and continuous transcription of its structural gene throughout the cell cycle of the eucaryote Chlorella.
Evidence supports the continuous availability of the carboxylase structural gene for transcription during the cell cycle of this eucaryote. Expand
Evidence for continuous availability of the phosphoribosylglycinamide synthetase structural gene for transcription during the cell cycle of the eucaryote Chlorella.
The linear pattern of accumulation of this stable enzyme and its change in rate of linear accumulation at the onset of DNA replication provide evidence that the structural gene of this enzyme is continuously available for transcription during the cell cycle, and that this gene is early replicating and is transcribed shortly after its replication. Expand
A temporal control of the de novo synthesis of isocitrate lyase during the cell cycle of the eucaryote Chlorella pyrenoidosa.
The cell division of Chlorella pyrenoidosa 211 8p can be synchronised by a regime of alternating 15 h illumination and 9 h darkness and the significance of the temporal control of de novo synthesis is discussed. Expand
Synthesis of enzymes during the cell cycle.
Enzyme measurements during the cell cycle coupled with genetic analysis provides new insights into the regulation of gene expression, which is useful for investigating the regulatory mechanisms operating in dividing cells. Expand
Induction of a reductive pathway for deoxyribonucleotide synthesis during early embryogenesis of the sea urchin.
Ribonucleotide reductase may, therefore, represent the first example of an enzyme system absent in unfertilized eggs that is produced in response to fertilization. Expand
Inhibition of Protein Synthesis by Cyclo-heximide (Actidione) in Chlorella
Cycloheximide is an antibiotic produced by Streptomyces griseus. It inhibits the growth of fungi1,2, algae3, protozoa4 and higher plants5, but has no effect on bacterial growth1. In yeast cells6,7Expand
Cooperation of mitochondrial and nuclear genes specifying the mitochondrial genetic apparatus in Neurospora crassa.
  • Z. Baráth, H. Küntzel
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1972
It is concluded that most, if not all, proteins of the mitochondrial genetic apparatus are coded by nuclear genes, synthesized on cytoplasmic ribosomes, and controlled by a repressor-like mitochondrial gene product. Expand
Contribution of mitochondrial protein synthesis to the formation of cytochrome oxidase in Locusta migratoria
The experiments presented here suggest that in the case of Locrtsta nzigratoria one polypeptide of cytochrome oxidase is also synthesized by mitochondrial ribosomes, and the electrophoretic mobility of this polyPEptide was found to be similar to the corresponding polypePTide from cyto chrome oxidase of Neurospora crassa. Expand