Transcript level of nucleostemin in newly diagnosed acute myeloid leukemia patients.

@article{You2013TranscriptLO,
  title={Transcript level of nucleostemin in newly diagnosed acute myeloid leukemia patients.},
  author={Yong You and Xiaoqing Li and Jine Zheng and Yaohui Wu and Yanli He and Wen ‐ Zhong Du and Ping Zou and Min Zhang},
  journal={Leukemia research},
  year={2013},
  volume={37 12},
  pages={1636-41}
}
To clarify the role of nucleostemin (NS) in AML, its transcription levels in bone marrow (BM) samples obtained from 128 newly diagnosed AML patients were analyzed. We determined that the highest NS transcription level was in M1 patients, while the lowest NS transcription level was in M3 patients. NS mRNA expression is positively correlated with blast percentages (%) and CD34, CD117 and CD123 antigen expression in BM samples but is unrelated to the transcription level of WT1. A significant… CONTINUE READING