Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.

  title={Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.},
  author={Uma T. Shankavaram and William C. Reinhold and Satoshi Nishizuka and Sylvia M. Major and Daisaku Morita and Krishna Chary and Mark A. Reimers and Uwe Scherf and Ari E Kahn and Douglas Dolginow and Jeffrey Cossman and Eric P. Kaldjian and Dominic A. Scudiero and Emanuel Petricoin and Lance A. Liotta and Jae K. Lee and John N. Weinstein},
  journal={Molecular cancer therapeutics},
  volume={6 3},
To evaluate the utility of transcript profiling for prediction of protein expression levels, we compared profiles across the NCI-60 cancer cell panel, which represents nine tissues of origin. For that analysis, we present here two new NCI-60 transcript profile data sets (A based on Affymetrix HG-U95 and HG-U133A chips; Affymetrix, Santa Clara, CA) and one new protein profile data set (based on reverse-phase protein lysate arrays). The data sets are available online at http://discover.nci.nih… CONTINUE READING

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