Transcranial magnetic stimulation: a historical evaluation and future prognosis of therapeutically relevant ethical concerns

@article{Horvath2010TranscranialMS,
  title={Transcranial magnetic stimulation: a historical evaluation and future prognosis of therapeutically relevant ethical concerns},
  author={Jared C. Horvath and Jennifer M Perez and Lachlan Forrow and Felipe Fregni and {\'A}lvaro Pascual-Leone},
  journal={Journal of Medical Ethics},
  year={2010},
  volume={37},
  pages={137 - 143}
}
Transcranial Magnetic Stimulation (TMS) is a non-invasive neurostimulatory and neuromodulatory technique increasingly used in clinical and research practices around the world. Historically, the ethical considerations guiding the therapeutic practice of TMS were largely concerned with aspects of subject safety in clinical trials. While safety remains of paramount importance, the recent US Food and Drug Administration approval of the Neuronetics NeuroStar TMS device for the treatment of specific… 
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References

SHOWING 1-10 OF 47 REFERENCES
Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research
Therapeutic application of repetitive transcranial magnetic stimulation: a review
Noninvasive human brain stimulation.
TLDR
The history and current applications of noninvasive brain stimulation, stimulation device design principles, the electromagnetic and physical foundations of the techniques, and the current knowledge about the electrophysiologic basis of the effects are reviewed.
Transcranial magnetic stimulation in neurology
Transcranial magnetic stimulation (TMS) in the treatment of major depression — a pilot study
TLDR
The data suggest that TMS might indeed have a relevant antidepressive efficacy and there was an improvement of depressive symptoms in both verum groups, more pronounced in the ‘stimulation below threshold’ group.
Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial
Handbook of Transcranial Magnetic Stimulation
TLDR
Unique aspects of TMS include its relative safety, ease of application and the awake and interactive state of the subject being stimulated.
Transcranial magnetic stimulation in patients with epilepsy
TLDR
The results do not support the view that TMS specifically activates the epileptic foci and induced a partial motor seizure from the contralateral hemisphere to the exclusive temporal focus in the only patient stimulated with 100% maximal intensity.
Transcranial Magnetic Stimulation Elicits Coupled Neural and Hemodynamic Consequences
TLDR
These results demonstrate long-lasting neural responses to TMS and support the use of hemodynamic-based neuroimaging to effectively monitor these changes over time.
Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996.
  • E. Wassermann
  • Psychology
    Electroencephalography and clinical neurophysiology
  • 1998
...
1
2
3
4
5
...