Transcranial direct current stimulation (tDCS) for post-traumatic stress disorder (PTSD): A randomized, double-blinded, controlled trial

  title={Transcranial direct current stimulation (tDCS) for post-traumatic stress disorder (PTSD): A randomized, double-blinded, controlled trial},
  author={Mohammad Javad Ahmadizadeh and Mehdi Rezaei and Paul B. Fitzgerald},
  journal={Brain Research Bulletin},

Treating Post-traumatic Stress Disorder with Neuromodulation Therapies: Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, and Deep Brain Stimulation

Overall, most studies reported favorable outcomes in alleviating both PTSD and depressive symptoms, and there has been considerable variation across trials regarding stimulation parameters, symptomatic response, and the role of adjunctive psychotherapy.

Variable symptomatic and neurophysiologic response to HD-tDCS in a case series with posttraumatic stress disorder.

  • B. HampsteadNathan Mascaro B. Martis
  • Psychology
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2019

Neuromodulation Treatments of Pathological Anxiety in Anxiety Disorders, Stressor-Related Disorders, and Major Depressive Disorder: A Dimensional Systematic Review and Meta-Analysis

There is moderate quality evidence for the efficacy of neuromodulation in treating pathological anxiety, and subgroup analyses revealed positive effects for TMS across disorders, and of focal neurommodulation in generalized anxiety disorder and PTSD.

Non-invasive brain stimulation for posttraumatic stress disorder: a systematic review and meta-analysis

Approximately 7–9% of people develop posttraumatic stress disorder in their lifetime, but standard pharmacological treatment or psychotherapy shows a considerable individual variation in their

Management of Chronic Pain and PTSD in Veterans With tDCS+Prolonged Exposure: A Pilot Study.

INTRODUCTION Chronic pain and posttraumatic stress disorder (PTSD) are prevalent comorbid conditions, particularly in Veterans; however, there are few integrated treatments for chronic pain and PTSD.

Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review

The evidence synthesised in this review suggests tDCS has the potential to reduce symptom severity in tinnitus and depression and further narrows down the number of potentially optimal stimulation parameters.

Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex for Treatment of Neuropsychiatric Disorders

Overall, tDCS stimulation of DLPFC could alleviate the clinical symptoms of schizophrenia, depression, drug addiction, attention deficit hyperactivity disorder and other mental disorders.



Working memory training with tDCS improves behavioral and neurophysiological symptoms in pilot group with post-traumatic stress disorder (PTSD) and with poor working memory

This pilot study investigated the feasibility of treating people suffering from both post-traumatic stress disorder (PTSD) and poor working memory by employing a combination of computerized working

Post-traumatic stress disorder: an evaluation of existing pharmacotherapies and new strategies

The need for improving pharmacotherapy of PTSD remains compelling and directions for further research are discussed, with concerns for side effects have limited frequent use of these.

A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation.

A systematic review and meta-analysis of tDCS clinical trials suggested that some AEs such as itching and tingling were more frequent in the tDCS active group, although this was not statistically significant and a revised adverse effects questionnaire is proposed to be applied in tDCS studies in order to improve systematic reporting of tCS-related AEs.

Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation.

The findings suggest anterior cingulate, frontal, and thalamic involvement in the neuronal circuitry underlying PTSD.

Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)

Network meta-analysis of 28 trials found paroxetine and topiramate to be more effective than most medications for reducing PTSD symptoms, but analysis was based largely on indirect evidence and limited to one outcome measure (low SOE).