Transcranial direct current stimulation: State of the art 2008

  title={Transcranial direct current stimulation: State of the art 2008},
  author={Michael A. Nitsche and Leonardo G. Cohen and Eric M. Wassermann and Alberto Priori and Nicolas Lang and Andrea Antal and Walter Paulus and Friedhelm Christoph Hummel and Paulo S. Boggio and Felipe Fregni and {\'A}lvaro Pascual-Leone},
  journal={Brain Stimulation},

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Spatiotemporal after-effects of transcranial direct current stimulation onsensory-evoked activity in rat S1: A pilot VSDI study

It was found that after repetitive anodal tDCS, sensory-evoked VSD responses were significantly increased in amplitude and spatial extent of activation, counteracting the sensory adaptation process observed in control rats.

Physiology of Transcranial Direct and Alternating Current Stimulation

An overview about physiological mechanisms of tDCS and tACS is provided, and their potential application in studies of brain function and cognition is reviewed.

Transcranial direct current stimulation (tDCS) – Application in neuropsychology

Reprint of: Transcranial direct current stimulation (tDCS) – Application in neuropsychology

Transcranial Direct Current Stimulation in Cognitive Neuroscience

The effects of tDCS are not restricted to the areas to which it is directly targeted; rather, tDCS can elicit network-level changes that are relevant to complex aspects of human cognition and behavior.

Physiological Basis of Transcranial Direct Current Stimulation

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The authors bring together the results from these pharmacological, neurophysiological, and imaging studies to describe their current knowledge of the physiological effects of tDCS, and the theoretical framework for how tDCS affects motor learning is proposed.

Transcranial direct current stimulation--update 2011.

This overview will deliver an update of the last two years of research, because especially during this time numerous important studies were published covering the above-mentioned fields.

Effects of transcranial direct current stimulation on steady-state visual evoked potentials

It is demonstrated that tDCS over occipital areas altered brain activity evoked by visual stimuli, and steady-state visual evoked potential (SSVEP) was referred to, a promising visual evokes potential that has been widely used in brain-computer interfaces.

Transcranial Direct Current Stimulation: Protocols and Physiological Mechanisms of Action

It will be discussed how specific stimulation parameters, like stimulation intensity, duration, electrode size, and configuration, including recently developed new stimulation protocols, determine the direction, magnitude, and duration of effects.



Manipulation of phosphene thresholds by transcranial direct current stimulation in man

The results show that tDCS elicits a transient, reversible excitability alteration of the visual cortex, thus representing a promising tool for neuroplasticity research.

Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression

Results from a preliminary double-blind, randomized, controlled study that evaluated the cognitive adverse effects of five sessions of tDCS of the left dorsolateral prefrontal cortex (DLPFC) in patients with major depression are reported.

Brain polarization in humans: a reappraisal of an old tool for prolonged non-invasive modulation of brain excitability

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  • 2003

Anticonvulsant Effects of Transcranial Direct‐current Stimulation (tDCS) in the Rat Cortical Ramp Model of Focal Epilepsy

To evaluate its anticonvulsant potential, transcranial direct current stimulation was tested in a modified cortical ramp‐stimulation model of focal epilepsy.

Oscillatory brain activity and transcranial direct current stimulation in humans

It is shown here that tDCS transiently and reversibly changed the organized cortical activity elicited by visual stimulation, which might be a suitable method to affect higher order cognitive processes.

Non‐synaptic mechanisms underlie the after‐effects of cathodal transcutaneous direct current stimulation of the human brain

The findings demonstrate that the after‐effects of tDCS have a non‐synaptic mechanism of action based upon changes in neural membrane function and could arise from alterations in transmembrane proteins and from electrolysis‐related changes in [H+] induced by exposure to constant electric field.

Transcranial direct current stimulation disrupts tactile perception

Cortical processing can be modulated in a behaviorally/perceptually meaningful way by weak transcranial current stimulation applied through portable technology, and offers a new perspective for the treatment of conditions characterized by alterations of cortical excitability.

Polarization of the human motor cortex through the scalp

It is concluded that such weak (< 0.5 mA) anodal scalp DC, alternated with a cathodal DC, significantly depresses the excitability of the human motor cortex, providing evidence that a small electric field crosses the skull and influences the brain.

Excitability changes induced in the human primary visual cortex by transcranial direct current stimulation: direct electrophysiological evidence.

PURPOSE Transcranial direct current stimulation (tDCS) has been shown to modify the perception threshold of phosphenes elicited by transcranial magnetic stimulation (TMS). The current study was