Transcranial Cortical Stimulation in the Treatment of Obsessive-Compulsive Disorders: Efficacy Studies
@article{Saba2015TranscranialCS, title={Transcranial Cortical Stimulation in the Treatment of Obsessive-Compulsive Disorders: Efficacy Studies}, author={Ghassen Saba and Albert Moukheiber and Antoine Pelissolo}, journal={Current Psychiatry Reports}, year={2015}, volume={17}, pages={1-8} }
Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are non-invasive brain stimulation methods that became widely used as therapeutic tools during the past two decades especially in cases of depression and schizophrenia. Low frequency rTMS and cathodal effect of tDCS inhibits cortical functioning while high frequency and anodal effect of tDCS have the opposite effect. Prolonged and repetitive application of either methods leads to changes in…
31 Citations
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Improved understanding of the therapeutic effects of rTMS in OCD will support fine-tuning of the method and help determine how to best optimize the approach via rT MS or dTMS to achieve clinically relevant results.
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Through the analysis of controlled studies, meta-analyses, and International treatment guidelines, the present article is aimed at providing the state of the art on the use of brain stimulation techniques for the treatment of OCD.
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The first report on a patient with treatment-refractory OC disorder treated with sertraline and an enhanced prefrontal tDCS protocol with a classic left-anodal/right cathodal montage experiencing a 22% reduction of OC symptoms as well as reduction in depression and anxiety symptoms is provided.
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- 2016
Low-frequency repetitive transcranial magnetic stimulation applied to the presupplementary area seems ineffective for the treatment of obsessive-compulsive disorder patients, at least in severe and drug-refractory cases such as those included in this study.
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Different brain stimulation techniques are promising as an add-on treatment of refractory OCD, although studies frequently reported inconsistent results.
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TREATMENT-RESISTANT OBSESSIVE COMPULSIVE DISORDER: AN EVALUATION STUDY OF THE AUGMENTATION EFFECT OF LOW-FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION
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It is concluded that low frequency rTMS is significantly effective as an adjunctive treatment for resistant OCD and that the SMA is the most effective brain target.
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