Transcobalamin II and its cell surface receptor.

  title={Transcobalamin II and its cell surface receptor.},
  author={Bellur Seetharam and Nan Li},
  journal={Vitamins and hormones},
Transcobalamin II (TC II), a nonglycoprotein secretory protein of molecular mass 43 kDa, and its plasma membrane receptor (TC II-R), a heavily glycosylated protein with a monomeric molecular mass of 62 kDa, are essential components of plasma cobalamin (Cbl; vitamin B12) transport to all cells. Evidence from studies over the past 10 years has provided some important information on their structure, regulation of expression, and function. Some of the specific findings include (a) identification of… CONTINUE READING

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