Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.

@article{Len2016TranscatheterOS,
  title={Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.},
  author={M. Ben{\'i}tez Le{\'o}n and Craig R Smith and Michael J. Mack and Raj R. Makkar and Lars Georg Svensson and Susheel K. Kodali and Vinod H. Thourani and Emin Murat Tuzcu and D. C. Miller and Howard C Herrmann and Darshan Doshi and David Jacques Cohen and Augusto D. Pichard and Samir R Kapadia and Todd M. Dewey and Vasilis C. Babaliaros and Wilson Y. Szeto and Mathew Russell Williams and Dean J Kereiakes and Alan Zajarias and Kevin L Greason and Brian K. Whisenant and Robert W. Hodson and Jeffrey W. Moses and Alfredo E. Trento and David L Brown and William Fuller Fearon and Philippe Pibarot and Rebecca T. Hahn and Wael Abdel Jaber and William N. Anderson and Maria C Alu and John G Webb},
  journal={The New England journal of medicine},
  year={2016},
  volume={374 17},
  pages={
          1609-20
        }
}
BACKGROUND Previous trials have shown that among high-risk patients with aortic stenosis, survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical aortic-valve replacement. We evaluated the two procedures in a randomized trial involving intermediate-risk patients. METHODS We randomly assigned 2032 intermediate-risk patients with severe aortic stenosis, at 57 centers, to undergo either TAVR or surgical replacement. The primary end point was death from any… CONTINUE READING

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