Transcatheter aortic valve replacement and standard therapy in inoperable patients with aortic stenosis and low EF.

@article{Passeri2015TranscatheterAV,
  title={Transcatheter aortic valve replacement and standard therapy in inoperable patients with aortic stenosis and low EF.},
  author={Jonathan J. Passeri and Sammy Elmariah and Ke Xu and Ignacio Inglessis and Joshua N. Baker and Maria C Alu and Susheel K. Kodali and Martin B. Leon and Lars Georg Svensson and Philippe Pibarot and William Fuller Fearon and Ajay J. Kirtane and Gus J. Vlahakes and Igor F. Palacios and Pamela Sylvia Douglas},
  journal={Heart},
  year={2015},
  volume={101 6},
  pages={463-71}
}
OBJECTIVES The aims of this study were to evaluate the effect of left ventricular (LV) dysfunction on clinical outcomes after transcatheter aortic valve replacement (TAVR) and standard therapy for severe aortic stenosis (AS) and to assess LV ejection fraction (LVEF) recovery and its impact on subsequent clinical outcomes. METHODS Cohort B of the Placement of AoRtic TraNscathetER Valves trial randomised 342 inoperable patients with severe AS to TAVR or standard therapy. We defined LV… CONTINUE READING