Transcardiac adiponectin gradient is independently related to endothelial vasomotor function in large and resistance coronary arteries in humans.

@article{Takano2006TranscardiacAG,
  title={Transcardiac adiponectin gradient is independently related to endothelial vasomotor function in large and resistance coronary arteries in humans.},
  author={H. Takano and Yasushi Kodama and Yoshinobu Kitta and Takamitsu Nakamura and Jyun-ei Obata and Akira Mende and Ken-ichi Kawabata and Yukio Saitoh and Daisuke Fujioka and Tsuyoshi Kobayashi and Hideyuki Hasebe and Kiyotaka Kugiyama},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={291 6},
  pages={
          H2641-6
        }
}
Adiponectin, an adipocyte-derived protein, has been shown to have vasculoprotective effects. This study examined the possible relationship between coronary vasomotor function and the transcardiac gradient of adiponectin, reflecting adiponectin utilization and/or accumulation in the coronary vascular bed. The epicardial diameter and blood flow response of the left anterior descending coronary artery to intracoronary infusions of ACh was analyzed in 108 consecutive subjects who had a normal… CONTINUE READING

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