Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain.

@article{Rush1998TransbilayerMO,
  title={Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain.},
  author={Jeffrey S. Rush and Klaus van Leyen and Ouathek Ouerfelli and Beata A Wolucka and Charles J. Waechter},
  journal={Glycobiology},
  year={1998},
  volume={8 12},
  pages={1195-205}
}
The results described in the accompanying article support the model in which glucosylphosphoryldolichol (Glc-P-Dol) is synthesized on the cytoplasmic face of the ER, and functions as a glucosyl donor for three Glc-P-Dol:Glc0-2Man9-GlcNAc2-P-P-Dol glucosyltransferases (GlcTases) in the lumenal compartment. In this study, the enzymatic synthesis and structural characterization by NMR and electrospray-ionization tandem mass spectrometry of a series of water-soluble beta-Glc-P-Dol analogs… CONTINUE READING
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The participation of lipid - linked oligosaccharide in the synthesis of membrane glycoproteins

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2 Excerpts

Use of water-soluble analogs to study the transbilayer movement of glucosylphosphoryldolichol and its function as a glucosyl donor in brain

  • J. S. Rush, K. van Leyen, O. Ouerfelli, B. Wolucka, C. J. Waechter
  • Glycobiology
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2 Excerpts

Determination of the anomeric configuration of glycosyl esters of nucleoside pyrophosphates and polyisoprenyl phosphates by fast-atom bombardment tandem mass

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1 Excerpt

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