Transarterial chemoembolization plus sorafenib: a sequential therapeutic scheme for HCV-related intermediate-stage hepatocellular carcinoma: a randomized clinical trial.

@article{Sansonno2012TransarterialCP,
  title={Transarterial chemoembolization plus sorafenib: a sequential therapeutic scheme for HCV-related intermediate-stage hepatocellular carcinoma: a randomized clinical trial.},
  author={Domenico Ettore Sansonno and Gianfranco Lauletta and Sabino Russi and Vincenza Conteduca and Loredana Sansonno and Francesco Dammacco},
  journal={The oncologist},
  year={2012},
  volume={17 3},
  pages={
          359-66
        }
}
BACKGROUND Recurrence of hepatocellular carcinoma (HCC) is a major problem after surgical or ablative treatments. The aim of this prospective, single-center, placebo-controlled, randomized, double-blind clinical study was to evaluate the effectiveness of transarterial chemoembolization (TACE) combined with sorafenib as a sequential treatment regimen in delaying time to progression (TTP) of intermediate-stage HCC in patients with chronic hepatitis C virus (HCV) infection. MATERIAL AND METHODS… CONTINUE READING
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