Transarterial Myoblast Transplantation in Dogs

  title={Transarterial Myoblast Transplantation in Dogs},
  author={Mark A Oyama and Valentina M Merola and Thomas E. Eurell},
Cardiac cellular transplantation seeks to replace cardiac myocytes irretrievably damaged by injury with adult progenitor cells capable of maturing into cardiac-like tissue. We sought to harvest and culture adult skeletal muscle myoblasts (satellite cells), to evaluate fluorescent labeling of myoblasts, and to develop a technique for cardiac cellular transplantation using a transcoronary arterial transplantation (TCAT) method in healthy dogs. Four adult purpose-bred dogs underwent skeletal… CONTINUE READING