Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells.

Abstract

In epithelial cells, the cell surface glycoprotein E-cadherin is a key molecule in the establishment of cell-cell adhesion. In addition to its contribution to cell adhesion, E-cadherin was found to induce ligand-independent activation of the EGF receptor (EGFR), likely as a result of their co-clustering. As it has also been reported that ligand activation… (More)

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Cite this paper

@article{Sovov2004TransactivationOE, title={Transactivation of E-cadherin is not involved in the activity of EGF receptor in colorectal carcinoma cells.}, author={Vlasta Sovov{\'a} and Dana Ku{\vc}erov{\'a} and Martina Vojtěchov{\'a} and Eva Sloncov{\'a} and Zdena Tuh{\'a}{\vc}kov{\'a}}, journal={International journal of oncology}, year={2004}, volume={25 5}, pages={1459-64} }