Transactions Between Substance Use Intervention, the Oxytocin Receptor (OXTR) Gene, and Peer Substance Use Predicting Youth Alcohol Use

@article{Cleveland2017TransactionsBS,
  title={Transactions Between Substance Use Intervention, the Oxytocin Receptor (OXTR) Gene, and Peer Substance Use Predicting Youth Alcohol Use},
  author={H. Harrington Cleveland and Amanda M. Griffin and Pedro Sofio Abril Wolf and Richard Wiebe and Gabriel L Schlomer and Mark E. Feinberg and Mark t. Greenberg and Richard L. Spoth and Cleve Redmond and David J. Vandenbergh},
  journal={Prevention Science},
  year={2017},
  volume={19},
  pages={15-26}
}
This study investigated the oxytocin receptor (OXTR) gene’s moderation of associations between exposure to a substance misuse intervention, average peer substance use, and adolescents’ own alcohol use during the 9th-grade. OXTR genetic risk was measured using five single nucleotide polymorphisms (SNPs), and peer substance use was based on youths’ nominated closest friends’ own reports of alcohol, cigarette, and marijuana use, based on data from the PROSPER project. Regression models revealed… CONTINUE READING

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