Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi.

@article{Colli1993TranssialidaseAU,
  title={Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi.},
  author={Walter Colli},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1993},
  volume={7 13},
  pages={1257-64}
}
  • Walter Colli
  • Published 1993 in
    FASEB journal : official publication of the…
Trypanosoma cruzi, the agent of Chagas' disease, an ailment characterized by a progressive chronic fibrotic myocarditis and degeneration of tissues that are innervated by the autonomic nervous system, is a voracious sialic acid eater from glycoconjugates of the surrounding medium. This is accomplished through an active trans-sialidase residing on the surface membrane of the trypomastigote stage, which is the parasite form that invades vertebrate cells. The existence of the enzyme was proposed… CONTINUE READING

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