Trans-neuronal regulation of cortical apoptosis in the adult rat olfactory system.

@article{Leung2003TransneuronalRO,
  title={Trans-neuronal regulation of cortical apoptosis in the adult rat olfactory system.},
  author={Carol Ho-Wing Leung and Donald A Wilson},
  journal={Brain research},
  year={2003},
  volume={984 1-2},
  pages={182-8}
}
Previous work has identified a population of neurons within the anterior piriform cortex that undergo rapid apoptosis following de-afferentation by olfactory bulbectomy in adult rats. The specific initiation signal for apoptosis in this paradigm is unknown, but may include an activity-dependent trans-neuronal cascade. The present report examined the effect of adult-onset unilateral naris occlusion, which reduces olfactory bulb afferent excitation of piriform cortex, on apoptosis (terminal… CONTINUE READING