Trans-genera reconstitution and complementation of an adhesion complex in Toxoplasma gondii.

  title={Trans-genera reconstitution and complementation of an adhesion complex in Toxoplasma gondii.},
  author={M S Huynh and Corinna Opitz and Lai-Yu Kwok and F. M. Tomley and Vern B Carruthers and Dominique Soldati},
  journal={Cellular microbiology},
  volume={6 8},
Eimeria tenella and Toxoplasma gondii are obligate intracellular parasites belonging to the phylum Apicomplexa. In T. gondii, the microneme protein TgMIC2 contains two well-defined adhesive motifs and is thought to be a key participant in the attachment and invasion of host cells. However, several attempts by different laboratories to generate a knockout (KO) of TgMIC2 have failed, implying that TgMIC2 is an essential gene. As Eimeria and Toxoplasma utilize the same mechanisms of invasion and… CONTINUE READING

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Toxoplasmic encephalitis in children

  • A. B. Sabin
  • JAMA
  • 1941
Highly Influential
3 Excerpts

and surface capping of microneme proteins in Eimeria tenella

  • V. B. Carruthers, L. D. Sibley
  • Mol Biochem Parasitol
  • 2002

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