Trans-activation of TRPV1 by D1R in mouse dorsal root ganglion neurons.

@article{Lee2015TransactivationOT,
  title={Trans-activation of TRPV1 by D1R in mouse dorsal root ganglion neurons.},
  author={Dong Woo Lee and Pyung Sun Cho and H. K. Lee and S. Lee and S. J. Jung and S. Oh},
  journal={Biochemical and biophysical research communications},
  year={2015},
  volume={465 4},
  pages={
          832-7
        }
}
  • Dong Woo Lee, Pyung Sun Cho, +3 authors S. Oh
  • Published 2015
  • Medicine, Chemistry
  • Biochemical and biophysical research communications
  • TRPV1, a ligand-gated ion channel expressed in nociceptive sensory neurons is modulated by a variety of intracellular signaling pathways. Dopamine is a neurotransmitter that plays important roles in motor control, cognition, and pain modulation in the CNS, and acts via a variety of dopamine receptors (D1R-D5R), a class of GPCRs. Although nociceptive sensory neurons express D1-like receptors, very little is known about the effect of dopamine on TRPV1 in the peripheral nervous system. Therefore… CONTINUE READING

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