Trans-Resveratrol Restores the Damages Induced by Organophosphate Pesticide-Monocrotophos in Neuronal Cells

@inproceedings{Kumar2013TransResveratrolRT,
  title={Trans-Resveratrol Restores the Damages Induced by Organophosphate Pesticide-Monocrotophos in Neuronal Cells},
  author={Vivek Kumar and Vinay Kumar Tripathi and Abhishek Kumar Singh and Mohathshim Lohani and Mohammed Kuddus},
  booktitle={Toxicology international},
  year={2013}
}
The restorative potential of trans-resveratrol (RV) was investigated in a rat neuronal cell line (PC12) exposed to organophosphate pesticide-monocrotophos (MCP). RV shows significant protection against MCP-induced alterations in PC12 cells by restoration of oxidative stress-mediated apoptosis and cytotoxicity. RV treatment significantly reduced reactive oxygen species (ROS) production and lipid peroxidation, and also restored glutathione levels and mitochondrial membrane potential, in cells… CONTINUE READING

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