Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.

@article{Palmer1989TransACPDAS,
  title={Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.},
  author={Edward J. Palmer and Daniel T Monaghan and Carl Cotman},
  journal={European journal of pharmacology},
  year={1989},
  volume={166 3},
  pages={585-7}
}
Excitatory amino acids (EAA) are thought to mediate their actions through at least five receptor subtypes. Four of these types appear to gate ion channels and have been named for agonists by which they are selectively activated: N-methyl-Daspartate (NMDA), kainate, a-amino-3-hydroxy5-methyl isoxazole-4-propionlc acid (AMPA), quisqualate and 2-amino-4-phosphonobutyrate (AP4). There is now compelling evidence from studies of phospholnositlde (PI) metabolism indicating that there is a fifth… CONTINUE READING