Tranilast ameliorates cyclophosphamide-induced lung injury and nephrotoxicity.

@article{Said2016TranilastAC,
  title={Tranilast ameliorates cyclophosphamide-induced lung injury and nephrotoxicity.},
  author={Eman Said and W. Elkashef and R. R. Abdelaziz},
  journal={Canadian journal of physiology and pharmacology},
  year={2016},
  volume={94 4},
  pages={
          347-58
        }
}
The world-wide increase in cancer incidence imposes a corresponding significant increase in the use of chemotherapeutic agents. Nephrotoxicity is a side effect frequently encountered with cyclophosphamide (CP), which is also well-known to cause acute and chronic lung toxicities. The current study focuses on the evaluation of the potential protective efficacy of tranilast against acute and subacute CP-induced lung and kidney injuries in male Swiss Albino mice. Intraperitoneal CP significantly… Expand
Boric acid protects against cyclophosphamide-induced oxidative stress and renal damage in rats.
  • M. Cengiz
  • Medicine
  • Cellular and molecular biology
  • 2018
Carvacrol attenuates cyclophosphamide-induced oxidative stress in rat kidney.
...
1
2
...

References

SHOWING 1-10 OF 59 REFERENCES
Tranilast reduces serum IL-6 and IL-13 and protects against thioacetamide-induced acute liver injury and hepatic encephalopathy.
Cyclophosphamide-induced nephrotoxicity, genotoxicity, and damage in kidney genomic DNA of Swiss albino mice: the protective effect of Ellagic acid
Intervention of astaxanthin against cyclophosphamide-induced oxidative stress and DNA damage: a study in mice.
Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy.
  • S. Tan, Yuan Zhang, A. Cox, D. Kelly, W. Qi
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2011
Tranilast ameliorates impaired hepatic functions in Schistosoma mansoni-infected mice
Viscum album L. extract and quercetin reduce cyclophosphamide-induced cardiotoxicity, urotoxicity and genotoxicity in mice.
Protection against Ovariectomy-Induced Bone Loss by Tranilast
...
1
2
3
4
5
...