Tranexamic acid versus ɛ-aminocaproic acid: efficacy and safety in paediatric cardiac surgery.

@article{Martin2011TranexamicAV,
  title={Tranexamic acid versus ɛ-aminocaproic acid: efficacy and safety in paediatric cardiac surgery.},
  author={Klaus Daniel Martin and Tam{\'a}s Breuer and Ralph Gertler and Alexander Hapfelmeier and Christian Schreiber and Ruediger Lange and John Hess and Gunther Wiesner},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2011},
  volume={39 6},
  pages={892-7}
}
OBJECTIVE Tranexamic acid (TXA) and ɛ-aminocaproic acid (EACA) are used for antifibrinolytic therapy in cardiac surgery, although data directly comparing their blood sparing effect and their side effects, especially in paediatric cardiac surgical patients, are still missing. METHODS We analysed perioperative data of 234 paediatric patients weighing less than 20 kg undergoing cardiac surgery. In a 5-month period, all patients (n=114) received TXA (group TXA). During a second 5-month period… CONTINUE READING
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