Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies

  title={Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies},
  author={Mohammad Taraz and S. Niknam and A. Ehsani},
  journal={Dermatologic Therapy},
Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to prevent abnormal fibrinolysis to reduce blood loss and exerts its effect by reversibly blocking lysine binding sites on plasminogen molecules, thus inhibiting plasminogen activator… Expand
24 Citations
Oral Tranexamic Acid for the Treatment of Melasma: A Review
Oral tranexamic acid for the treatment of melasma
  • F. Ali
  • Medicine
  • Clinical and experimental dermatology
  • 2019
New oral and topical approaches for the treatment of melasma
Tranexamic Acid for Melasma: Evaluating the Various Formulations.
Evaluation of oral tranexamic acid in the treatment of melasma
Chemical peeling for acne and melasma: current status and innovations.
  • C. Conforti, I. Zalaudek, +5 authors C. Dianzani
  • Medicine
  • Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia
  • 2019


Treatment of Melasma With Oral Administration of Tranexamic Acid
Topical tranexamic acid as a promising treatment for melasma
  • B. Ebrahimi, F. Naeini
  • Medicine
  • Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
  • 2014
The treatment of melasma: a review of clinical trials.
Localized Intradermal Microinjection of Tranexamic Acid for Treatment of Melasma in Asian Patients: A Preliminary Clinical Trial
  • Ji Ho Lee, Jong G Park, +4 authors Y. M. Park
  • Medicine
  • Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2006
Oral tranexamic acid in treatment of melasma in Pakistani population: a pilot study
Oral tranexamic acid for the treatment of melasma.
Oral tranexamic acid (TA) in the treatment of melasma: A retrospective analysis.
Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
Melasma. Classification and treatment