Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies

@article{Taraz2017TranexamicAI,
  title={Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies},
  author={Mohammad Taraz and S. Niknam and A. Ehsani},
  journal={Dermatologic Therapy},
  year={2017},
  volume={30}
}
Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to prevent abnormal fibrinolysis to reduce blood loss and exerts its effect by reversibly blocking lysine binding sites on plasminogen molecules, thus inhibiting plasminogen activator… Expand
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