Tranexamic acid in trauma: how should we use it?

@article{Napolitano2013TranexamicAI,
  title={Tranexamic acid in trauma: how should we use it?},
  author={Lena M. Napolitano and Mitchell J. Cohen and Bryan A. Cotton and Martin A. Schreiber and Ernest Eugene Moore},
  journal={The journal of trauma and acute care surgery},
  year={2013},
  volume={74 6},
  pages={
          1575-86
        }
}
T CRASH-2 trial results have prompted trauma centers to contemplate whether tranexamic acid (TXA) should be added to their armamentarium for the treatment of bleeding trauma patients. Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of trauma (ACOT). Furthermore, some studies have documented that the risk of death in trauma correlates significantly with fibrinolysis. The presence of hyperfibrinolysis (HF) in patients with severe traumatic injuries is associated… CONTINUE READING

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