Tranexamic Acid Treatment for Heavy Menstrual Bleeding: A Randomized Controlled Trial

@article{Lukes2010TranexamicAT,
  title={Tranexamic Acid Treatment for Heavy Menstrual Bleeding: A Randomized Controlled Trial},
  author={Andrea S. Lukes and Keith A. Moore and Kenneth N. Muse and Janet K Gersten and Bryan R. Hecht and M{\aa}ns Edlund and Holly E. Richter and Scott Evan Eder and George R. Attia and Donald Patrick and Arkady Rubin and Gary A. Shangold},
  journal={Obstetrics \& Gynecology},
  year={2010},
  volume={116},
  pages={865-875}
}
OBJECTIVE: To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding. METHODS: Adult women with heavy menstrual bleeding (mean menstrual blood loss 80 mL or more per cycle) were enrolled in a double-blind, placebo-controlled study. After two pretreatment menstrual cycles, women were randomized to receive tranexamic acid 3.9 g/d or placebo for up to 5 days per menstrual cycle through six cycles. To meet the prespecified three… Expand

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